To implement a novel method of investigation of electromagnetic field action on state of cell nucleus the simulation of irradiation of the cells of human buccal epithelium by electromagnetic field of EMF band is carried out. The cells were exposed to radiation of frequency f = 36.64 GHz, with power densities W = 10^–1, 1 and 4 W/m² during 10 seconds. To answer on the question of existence of nonthermal biological effect of electromagnetic field onto living cells the specific absorption rate (SAR) of a solution that contained cells is calculated. The numerical simulation based on FDTD method permitted to take into account different parts of experimental setup to obtain real distribution of electromagnetic field inside irradiated solution.